Stem Cells and Cancer Journal Club

Stem Cells and Cancer Journal Club meetings take place on Thursdays during the spring semester. This journal club addresses aspects of basic cell and developmental stem cell biology (using all model organisms), cancer, and the connections linking stem cells with cancer and aging. All are welcome to attend. The journal club is offered as BIOMG 7940/7800 to students enrolled in the Stem Cell Biology Minor. Course Description.

Upcoming Presentations

There are no upcoming presentations at this time.

Recent Presentations

DATE	PRESENTERS
May 4, 2023	Facilitator: Dr. Carrie Adler Paper: Embryonic origins of adult pluripotent stem cells. Kimura et al.
April 13, 2023	Facilitator: Andrew White Paper: Nature. 2022. A cellular hierarchy in melanoma uncouples growth and metastasis. Karras et al.
March 16, 2023	Facilitator: Ben Cosgrove Paper: Nature. 2022. Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration. Moiseeva et al.
February 23, 2023	Facilitator: Ellie Duan Stem Cell Stem. 2021. Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency. Kinoshita et al.
February 9, 2023	Introduction to Stem Cells by Dr. Gerlinde Van de Walle.
May 5, 2022	Paper: Dev Cell. 2022. Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy. Xie et al.
April 21, 2022	Paper: Bioeng Transl Med. 2022. In-cytoplasm mitochondrial transplantation for mesenchymal stem cells engineering and tissue regeneration. Yao et al.
March 24, 2022	Preprint: bioRxiv. 2021. Krüppel-like factor 4 is required for development and regeneration of germline and yolk cells from somatic stem cells in planarians. Issigonis et al.
February 17, 2022	Paper: Cell Stem Cell. 2018. Muscle stem cells exhibit distinct clonal dynamics in response to tissue repair and homeostatic aging. Tierney et al.
January 27, 2022	Introduction to stem cells by Gerlinde Van de Walle.
May 13, 2021	Paper: eLife. 2020. Functionally heterogeneous human satellite cells identified by single cell RNA sequencing. Barruet et al.
April 29, 2021	Paper: Oncogene. 2020. Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma. Nimmakayala et al.
April 15, 2021	Paper: Cell Metabolism. 2021. Platelets Facilitate the Wound-Healing Capability of Mesenchymal Stem Cells by Mitochondrial Transfer and Metabolic Reprogramming. Levoux et al.
March 18, 2021	Paper: Cell Stem Cell. 2018. Paneth Cell Multipotency Induced by Notch Activation following Injury. Yu et al.
February 18, 2021	Introduction to stem cells by Gerlinde Van de Walle.
April 30, 2020	Paper: Cell Stem Cell. 2017. Intestinal enteroendocrine lineage cells possess homeostatic and injury-inducible stem cell activity. Yan et al.
April 16, 2020	Paper: Nature Medicine. 2014. STAT3 signaling controls satellite cell expansion and skeletal muscle repair. Tierney et al.
February 27, 2020	Paper: Nature Communicatons. 2020. SP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumor. Song et al.
January 23, 2020	Introduction to stem cells and exploration in regenerative medicine by Gerlinde Van de Walle.
May 2, 2019	Student Presenters: Ian Rose & Max Kushner, Moderator: Andrew White Nature. 2018. A slow-cycling LGR5 tumour population mediates basal cell carcinoma relapse after therapy. Sanchez-Danes et al.
April 11, 2019	Student Presenters: Mallikarjun Bidarimath & Dahihm Kim, Moderator: Gerlinde Van de Walle Cell Stem Cell. 2018. Reciprocal signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression. Wang et al.
March 14, 2019	Student Presenters: Chelsea Stephens & Lucia Borlle, Moderator: Ben Cosgrove Cell Stem Cell. 2018. Muscle stem cells exhibit distinct clonal dynamics in response to tissue repair and homeostatic aging. Tierney et al.
February 21, 2019	Student Presenter: Amy Hung, Moderator: Praveen Sethupathy Cell Stem Cell. 2017. Intestinal enteroendocrine lineage cells possess homeostatic and injury-inducible stem cell activity. Yan et al.
January 24, 2019	Lecture on stem cells by Praveen Sethupathy, and introduction to experimental methods in stem cell science.
May 3, 2018	Student Presenter: Sam Rosenberg, Moderator: Praveen Sethupathy Nature Cell Biology. 2014. MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. Hwang et al.
April 12, 2018	Student Presenter: Robert Yamulla, Moderator: Sunny Moon Cell Stem Cell. 2017. Melanocyte Stem Cell Activation and Translocation Initiate Cutaneous Melanoma in Response to UV Exposure. Moon et al.
March 15, 2018	Student Presenters: Adam Francisco & Seona Lee, Faculty Moderator: Dan Berry Nature Cell Biology. 2012. Programming human pluripotent stem cells into white and brown adipocytes. Ahfeldt et al.
February 22, 2018	Student Presenters: Benjamin Cohen & Jon Villanueva, Faculty Moderator: Ben Cosgrove Cell. 2016. Autonomous Extracellular Matrix Remodeling Controls a Progressive Adaptation in Muscle Stem Cell Regenerative Capacity during Development. Tierney et al.
January 25, 2018	Student Presenter: Yu-Han Amy Hung, Faculty Moderator: Praveen Sethupathy Cell Stem Cell. 2017. Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity. Yan et al.
May 4, 2017	Student Presenters: Divya Shiroor & Robert Yamulla, Faculty Moderator: John Schimenti Science. 2016. Tissue damage and senescence provide critical signals for cellular reprogramming in vivo. Mosteiro et al.
April 13, 2017	Student Presenters: Tara Hall & Prachi Jain, Faculty Moderator: Tudorita Tumbar Nat Med. 2016. Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity. Burridge et al.
March 16, 2017	Student Presenters: Julio Sanchez & Yun Ha Hur, Faculty Moderator: Scott Coonrod Cell Stem Cell. 2017. Adaptive chromatin remodeling drives glioblastoma stem cell plasticity and drug tolerance. Liau et al.
February 16, 2017	Student Presenters: Miguel Brieno Enriquez & Jiahn Choi, Faculty Moderator: Ankur Singh Cell Stem Cell. 2016. Mesenchymal inflammation drives genotoxic stress in hematopoietic stem cells and predicts disease evolution in human pre-leukemia. Zambetti et al.
January 26, 2017	Student Presenters: Benjamin Cohen & Aditi Iyengar, Faculty Moderator: Sergiy Libert Nature. 2016. CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells. Dever et al.
May 5, 2016	Student Presenters: Blaine Harlan & Ian Rose, Faculty Moderator: Gerlinde Van de Walle Cell. 2016. Core circadian clock genes regulate leukemia stem cells in AML. Puram et al.
April 21, 2016	Student Presenters: Wilfred Leung & Melissa McDowell, Faculty Moderator: Kristy Richards Cancer Cell. 2015. Mist1 expressing gastric stem cells maintain the normal and neoplastic gastric epithelium and are supported by a perivascular stem cell niche. Hayakawa et al.
March 17, 2016	Student Presenter: Alex Loiben, Faculty Moderator: Ben Cosgrove Nature. 2016. Autophagy maintains stemness by preventing senescence. Garcia-Prat et al.
February 18, 2016	Student Presenter: Jordana Bloom, Faculty Moderator: Scott Coonrod Cell Stem Cell. 2015. Directly reprogrammed human neurons retain aging-associated transcriptomic signatures and reveal age-related nucleocytoplasmic defects. Mertens et al.
January 28, 2016	Student Presenter: Tim Pierpont, Faculty Moderator: Andrew White Cell Stem Cell. 2015. Regeneration of thyroid function by transplantation of differentiated pluripotent stem cells. Kurmann et al.
May 7, 2015	Student Presenter: Michael Platov, Faculty Moderator: Andrew White Cell Stem Cell. 2014. hPSC-derived maturing GABAergic interneurons ameliorate seizures and abnormal behavior in epileptic mice. Cunningham et al.
April 23, 2015	Student Presenter: Sally Ness, Faculty Moderator: Andrew Miller Gastroenterology. 2015. Helicobacter pylori activate and expand Lgr5+ stem cells through direct colonization of the gastric glands. Sigal et al.
March 19, 2015	Student Presenter: Melissa McDowell, Faculty Moderator: Scott Coonrod Nature. 2014. Oestrogen increases haematopoietic stem-cell self-renewal in females during pregnancy. Nakada et al.
February 19, 2015	Student Presenter: Robert Yamulla, Faculty Moderator: Alexander Nikitin Nature. 2014. Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. McCracken et al.
January 22, 2015	Student Presenter: Darshil Patel, Faculty Moderator: Robert Weiss Nature. 2014. Intracellular a-ketoglutarate maintains the pluripotency of embryonic stem cells. Carey et al.
May 8, 2014	Tim Pierpont (Weiss Lab) Cell. 2014. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Suva et al.
April 17, 2014	Benjmain Gordon (undergrad) Cell. 2014. Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer. Mori et al.
March 20, 2014	Dah-Jiun Fu (Nikitin Lab) Cell. 2013. Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling. He et al.
February 20, 2014	Alex Wang (Tumbar Lab) Nature. 2013. Dedifferentiation of committed epithelial cells into stem cells in vivo. Tata et al.
January 23, 2014	Amy Lyndaker (Weiss Lab) Nature. 2013. Reprogramming in vivo produces teratomas and iPS cells with totipotency features. Abad et al.
December 19, 2013	Prachi Jain (Tumbar Lab) Nat. Med. 2014. Self-renewal as a therapeutic target in human colorectal cancer. Kreso et al.