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Stem Cell Club

Upcoming Schedule

Stem Cell Club meetings take place each third Tuesday in Lecture Hall III of the Veterinary Research Tower from 12:00 p.m. to 1:00 p.m.

DATE PRESENTERS
February 18, 2014 Jun Kelly Liu
Nicolas Buchon
March 18, 2014 Brian Rudd
Daniel Barbash
April 15, 2014 Robert Weiss
Scott Coonrod


Recent Presentations

DATE PRESENTERS
January 21, 2014

Jayhun Lee (Tumbar Lab)
Hair follicle stem cell quiescence is associated with low epigenetic identity and high genome plasticity mediated by growth factor signaling

Maureen Lynch (Fischbach Lab)
3D culture models for investigating the effects of mechanical loading on osteogenic stem cell differentiation in breast cancer bone metastasis

December 17, 2013

Ankur Singh
Adhesive signature-based, label-free isolation of human pluripotent stem cells

Alexander Nikitin & Warren Zipfel
Stem cell pathology, imaging and the Stem Cell Core

November 19, 2013

Cait Costello (March Lab)
Synthetic small intestines for studies of host-microbe interactions

John Schimenti
Genome editing in mice and the Stem Cell Core

October 15, 2013

Leen Bussche (Van de Walle Lab)
A comparative stem cell model for breast cancer

Wendy Mercer Geil (Yen Lab)
Nuclear Raf-1 kinase regulates BLR1/CXCR5 promoter by binding to NFATc3 to control retinoic acid-induced leukemic cell differentiation

September 17, 2013

Xiling Shen
MicroRNA versatility in cell fate determination

Ian Welsh (Kurpios Lab)
From tissues to chromosomes, the developmental genomics of organ asymmetry

May 21, 2013

Brian Rudd
Neonatal immunity and the layered immune hypothesis

Young Hye Song (Fischbach Lab)
Adipose-derived stem cells as physicochemical regulator of tumor angiogenesis

April 16, 2013

Laura Hockaday (Butcher Lab)
In-Situ photocrosslinking and 3D bioprinting of defined matrix environments to control differentiation of adipose derived mesenchymal stem cells within tissue engineered heart valves

Kim Holloway (Cohen Lab)
Investigating regulatory pathways involved in mammalian meiosis and gametogenesis

March 19, 2013

Patricia Davidson (Lammerding Lab)
Using patient-derived iPSCs to investigate cardiac disease caused by lamin and titin mutations

Patrick Murphy (Soloway Lab)
Analysis of cell type specific epigenetic mark coordination using single molecule methods

February 19, 2013

Timothy Pierpont (Weiss Lab)
Elucidation of the DNA damage response and stem cell properties of murine metastatic testicular germ cell cancer

Iris Jonkers (Lis Lab)
The dynamics of RNA polymerase II in the transcription cycle

January 15, 2013

Brooke Wilson (Fortier Lab)
Novel use of a microfluidics device to identify the optimal biologic to enhance endogenous stem cell recruitment and homing

Yunhai Luo (Schimenti Lab)
Primordial germ cell depletion in FANCM-deficient mice involves p53-p21 signaling

December 18, 2012

Aiko Sada Nishimura (Tumbar Lab)
Defining the cellular lineage hierarchy in adult skin epidermis

Holly Jensen (Yen Lab)
Overcoming the differentiation block: Understanding retinoic acid-induced differentiation in a model human leukemic progenitor cell line

November 20, 2012

Andrea Flesken-Nikitin (Nikitin Lab)
Identification of a novel cancer-prone stem cell niche for the ovarian surface epithelium

Qiaoming Long
Role of SEL1L in liver cholesterol metabolism and tumorigenesis

October 16, 2012

Nicolas Buchon
Epithelium renewal in the Drosophila gut: how intestinal stem cells behave in a microbial world

Xiling Shen
Pattern formation in intestinal crypts

September 18, 2012

Lawrence Bonassar
Marrow-derived stem cells for intervertebral disc tissue engineering

Scott Coonrod
Linking structure to function in the mammalian oocyte cytoplasm

May 15, 2012

Vikas Ghai (Liu Lab)
Investigating the role of SEM-4/SALL in proliferation versus differentiation decisions during development of C. elegans postembryonic mesoderm

Tim Cowley (Lee Lab)
Elucidating the roles of mammalian HCF-1 and HCF-2 in beta-cell and embryonic stem cell function

April 17, 2012

Ute Schwab (Felippe Lab)
Establishing culture conditions favorable for equine B lymphopoiesis

Iris Jonkers (Lis Lab)
The role of P-TEFb in the RNA Polymerase II transcription cycle

March 20, 2012

Vimal Selvaraj
Directing differentiation of embryonic stem cells to oligodendrocytes

Jonathan Flax (Soloway Lab)
The role of DNA methylation in alternative splicing

February 21, 2012

Bo Ri Seo (Fischbach Lab)
Obesity-associated adipose stromal cells as physicochemical modulators of breast tumorigenesis

Ewelina Bolcun-Filas (Schimenti Lab)
Quality control in germ cells

January 17, 2012

Jayhun Lee (Tumbar Lab)
Epigenetic regulation of hair follicle stem cell proliferation during adult skin homeostatis

Yogindra Vedvyas (Jin Lab)
Development of mAb against Ephrin-B2: Application to detection of tumor, tumor-vasculature, and cancer stem cells

December 20, 2011

Amy Lyndaker (Weiss Lab)
A novel mouse model of testicular cancer: Simultaneous Pten loss and Kras activation in postnatal germ cells results in teratocarcinogenesis

Xuesen Zhang (Coonrod Lab)
PAD2-catalyzed histone Arginine 26 citrullination facilitates E2-reguated gene transcription

November 15, 2011

Iris Sun (Qi Lab)
ATP-P2X7 signaling is dispensable for inflammasome activation in adipose tissue in obesity

Aparna Mahadevan (Kurpios Lab)
Role of left-right signaling pathway in organ specific vascularization of the midgut

October 18, 2011

Chang-il Hwang (Nikitin Lab)
mir-34 deficiency increases cell proliferation but not iPS cell reprogramming efficiency

Laura Hockaday (Butcher Lab)
3D printed heterogeneous microenvironments: Gradient stiffness hydrogels for directed stem cell differentiation

May 17, 2011

Ashlee Watts (Nixon Lab)
Characterization and musculoskeletal application of pluripotent ESC-like cells derived from fetal tissue

Yunhai Luo (Schimenti Lab)
Genome Maintenance in germline stem cells

April 19, 2011

Adam Francisco (Long Lab)
Haploid Insufficiency of Suppressor Enhancer Lin12 1 Like (SEL1L) Predisposes Mice to High Fat Diet-induced Hyperglycemia

Julia Felippe
B cell differentiation from hematopoietic stem cells

March 15, 2011

Chieh-Yang Cheng (Nikitin Lab)
Role of neuroendocrine cells in prostate development

Michael Kotlikoff
Cardiac renewal - stem cells or dedifferentiation

February 15, 2011 Boram Kim (Coonrod Lab)
Role for MATER in Organelle Redistribution During Oocyte Maturation
Ian Welsh (Kurpios Lab)
A functional genomics approach to understand the transcriptional and signaling regulation of cellular behavior
January 18, 2011 Emily Chandler (Fischbach Lab)
Adipose progenitor cells and their role in breast tumorigenesis
James Hagarman (Soloway Lab)
Mutual antagonism between DNA methylation and H3K27 trimethylation in mouse ES cells
December 21, 2010 Iris Jonkers (Lis Lab)
Genome wide distribution of RNA polymerase II after inhibition of P-TEFb
Heather Flores (Aquadro/Barbash Labs)
Evolutionary analysis of the Drosophila bag of marbles gene elucidates both intraspecific function and the consequences of interspecific divergence
November 16, 2010 Xiling Shen
"Assymetric Division of Colon Cancer Stem Cells
Rodica Buncaciu (Yen Lab)
"AhR promotes retinoic acid-induced differentiation by decreasing Oct4 expression in human myeloblastic leukemia cells (HL-60) "
October 19, 2010 Lauren Schabel (Fortier Lab)
"iPS cells from mouse, dog and horse
Amy Lyndaker (Weiss Lab)
"Recurrent copy number variation and intact DNA damage signaling in 129-Dnd1Ter/Ter murine testicular teratomas "
September 21, 2010 Ling Qi
"The role of myeloid progenitor cells in obesity and diabetes"
Karin Lilja (Tudorita Tumbar Lab)
"Runx1 promotes tumorigenesis through a p21 mediated pathway in skin "
May 18, 2010 David Infanger (Claudia Fischbach Lab)
"Engineering 3D microenvironments to study brain tumor stem cell behavior"
Sophy Jesty (Michael Kotlikoff Lab)
"The role of cardiovascular precursor cells in cardiac repair after infarction"
April 20, 2010 Le Cheng (Alexander Nikitin Lab)
"The role of miR-376b/467b - cIAP1/2 pathway in mammary cancer stem cells"
Terri Iwata (Sylvia Lee Lab)
"A possible role for HCF1 and HCF2 in stem cell function"
March 16, 2010 Josh Waterfall (John Lis Lab)
"Tracking RNA polymerase genome-wide by sequencing nascent transcripts"
Jiajie Yu (John March Lab)
"Towards an in vitro intestine: Developing 3D epithelial cell culture"
February 16, 2010 Jun Kelly Liu
"Diversification of the C. elegans postembryonic mesoderm by a FoxF/C forkhead protein and a Six2 homeodomain protein"
Nokyoung Park (Dan Luo Lab)
"A cell free protein producing gel"
January 19, 2010 Rui Kan (Scott Coonrod Lab)
"Regulation of Oocyte Microtubule and Organelle Dynamics by PADI6 and the Cytoplasmic Lattices"
Moonsoo Jin
"Multi-scale Approach to Human Health: Targeting cancer, inflammation, and association between them "
December 15, 2009 Ryan Tasseff (Andrew Yen Lab)
"Modeling and Analysis of the Pathways Governing RA Induced Differentiation in Uncommitted Precursor Cells"
Alexander Nikitin
"State of the Stem Cell Program"
November 17, 2009 Song Eun Lee (Tudorita Tumbar Lab)
"The role of Runx1 in hair follicle stem cells during tissue homeostasis"
Kenneth Kemphues
"The C. elegans embryo: a model for asymmetric division"
October 20, 2009 Yin He (Ling Qi Lab)
"The IRE1a/XBP1 pathway of the UPR is required for adipogenesis"
Tunde Babalola (Larrry Bonassar Lab)
"Differential response of chondrocytes and MSCs to the dynamic loading"
September 15, 2009 Suzanne Hartford (John Schimenti Lab)
"DNA Repair and Replication Genes and their involvement in Spermatogonial Stem Cell Maintenance"
Heather Flores (Daniel Barbash/Chip Aquadro Labs)
"Testing the functional consequences of adaptive protein evolution at the drosophila germline stem cell regulatory gene bag of marbles"
May 18, 2009 Emily Chandler (Claudia Fischbach Lab)
"Microenvironmental cues at the breast cancer interface alter adipocyte progenitor cell function"
Qiaoming Long
"Control of Notch signaling and Pancreatic Development"
April 20, 2009 Paul Soloway
"Single Molecule Chromatin Analysis - A Tool for Stem Cell Research"
Irene Min (John Lis Lab)
"Genome-wide Analysis of Engaged RNA Polymerase Activity and Promoter Status in Stem Cells"
March 16, 2009 Mike Kotlikoff
"Role of stem cells in repair of the adult heart"
Huseyin C. Yalcin (Jonathan Butcher Lab)
"Simulated embryonic environmental conditions on stem cell differentiation towards cardiac phenotypes"
February 16, 2009 Alex Travis
"Using Stem Cells to Develop Canine Transgenesis--Soliciting the Audience's Feedback on our Data and My R01 Proposal"
W. Lee Kraus
"Signaling, Chromatin, and Transcription: Mechanisms in Search of a Model System"
January 19, 2009 Le Cheng (Alexander Nikitin Lab)
"Genomic instability in cancer stem cells"
Miaoqing Shen (Andrew Yen Lab)
"c-Cbl interacts with CD38 and promotes RA-induced differentiation and G0 arrest of human myeloblastic leukemia cells"
December 16, 2008 Kelly Liu
"Mesodermal patterning and diversification in C. elegans"
Joanna Krzyspiak (John March Lab)
"Recreating In Vivo Epithelial Behavior Using Stem Cells in a Microfluidic Platform"
November 18, 2008 Scott Coonrod
"Epigenetic Regulation of Preimplantation Development and Breast Cancer"
Lisa Fortier
"The Use of Magnetic Activated Cell Sorting for Enrichment of Equine Bone Marrow Derived Stromal Cells"
October 21, 2008 Ying Zhang (Tudorita Tumbar Lab)
"Temporal and spatial segregation of differentiation and self-renewal for adult hair follicle stem cells"
Siu Sylvia Lee
"Probing a role of the longevity gene hcf-1 in stem cell maintenance"
September 16, 2008 Jin Hyang Choi (Alexander Nikitin Lab)
"Role of the local dermal progenitor cells in sarcomagenesis associated with p53 and Rb inactivation"
Weipeng Mu (John Schimenti Lab)
"The essentiality of PDCD2 in mouse preimplantation development implicates its involvement in embryonic stem cell self-renewal"
May 20, 2008 Paula Cohen
"Investigating the determinants of normal gametogenesis in the mouse: meiosis and beyond"
Xia Xu (Robert Weiss Lab)
"A mouse model for lung cancer and possible roles for lung stem cells in tumor initiation"
April 15, 2008 Paul Soloway
"Epigenetic Reprogramming in the Mouse Germline"
Emily Chandler (Claudia Fischbach Lab)
"Adipocyte Precursor Cells and Their Role in Breast Cancer Malignancy"
March 18, 2008 Qiaoming Long
"Sel1L, the mammalian ortholog of the C. elegans sel-1 gene, is required for growth and expansion of pancreatic stem cells"
Leighton Core (John Lis Lab)
"Classification of transcription regulatory mechanisms by genome-wide analysis of transcriptionally engaged RNA polymerases"
February 19, 2008 Jonathan Butcher
"Mechanical regulation of cell differentiation and tissue morphogenesis - The playground of embryonic development"
James Lee Smith II
"Cytometric analysis of Raf1 localization and phosphorylation during retinoic acid induced differentiation of HL60 cells"
January 15, 2008 Andrew Yen
"Decisions, Decisions: Multiplication and Division for Making Change; ie., Retinoic acid, cell proliferation and differentiation"
Catherine Radcliffe (Lisa Fortier Lab)
"Defining a Molecular Marker Profile for Equine Mesenchymal Stem Cells"
December 18, 2007 Alyson Spealman (Michael Kotlikoff Lab)
"Isolation, Expansion, and Differentiation of Cardiac Precursor Cells from c-kitBAC-EGFP Mice"
Rebecca Holmes (Paula Cohen Lab)
"Meiosis and the Argonautes"
November 20, 2007 Yung-Hao Ching (John Schimenti Lab)
"Plzf : polydactyly and male germ cell depletion"
Yeunhee Kim (Alex Travis Lab)
"Stem cell-based technologies of assisted reproduction in the cat and dog"
September 18, 2007 Le Cheng (Alex Nikitin Lab)
"Mammary stem cells and cancer"
Karen Osorio (Doina Tumbar Lab)
"Hair follicle stem cell activation"
August 11, 2007 Lawrence Bonassar
"Research overview"
Warren Zipfel
"Research overview"
John Schimenti
"Research overview"
Alex Travis
"Research overview"
July 16, 2007 Alan Nixon
"Research overview"
Andrea Quaroni
"Research overview"
Watt Webb
"Research overview"
Bob Weiss
"Research overview"
June 18, 2007 Claudia Fischbach
"Research overview"
Lisa Fortier
"Research overview"
Mike Kotlikoff
"Research overview"
Alex Nikitin
"Research overview"
Doina Tumbar
"Research overview"

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